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SLC22A6 Antikörper

SLC22A6 Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498567
  • Target Alle SLC22A6 Antikörper anzeigen
    SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
    Reaktivität
    • 45
    • 21
    • 16
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human, Ratte, Maus
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SLC22A6 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 22
    • 21
    • 13
    • 8
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of OAT1 protein. (region surrounding Leu304)
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Reinheit
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product SLC22A6 Primärantikörper
  • Applikationshinweise
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
    Andere Bezeichnung
    SLC22A6 / OAT1 (SLC22A6 Produkte)
    Synonyme
    HOAT1 antikoerper, OAT1 antikoerper, PAHT antikoerper, ROAT1 antikoerper, NKT antikoerper, Oat1 antikoerper, Orctl1 antikoerper, mOat1 antikoerper, slc22a6 antikoerper, zgc:77073 antikoerper, SLC22A6 antikoerper, Paht antikoerper, Roat1 antikoerper, nkt antikoerper, oat1 antikoerper, oat1-B antikoerper, paht antikoerper, roat1 antikoerper, slc22a6-B antikoerper, Slc22a6 antikoerper, solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6, like antikoerper, Solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 S homeolog antikoerper, SLC22A6 antikoerper, Slc22a6 antikoerper, slc22a6l antikoerper, s22a6 antikoerper, slc22a6.S antikoerper
    Hintergrund
    SOAT1 (sterol O-acyltransferase 1), also designated ACAT1, is a homotetrameric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long-chain fatty acyl coenzyme A. The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol Oacyltransferase 2), also known as ACAT2 (acyl coenzyme A), participates in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the ER of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.Synonyms: Organic anion transporter 1, PAH transporter, PAHT, ROAT, Renal organic anion transporter 1, Solute carrier family 22 member 6
    Molekulargewicht
    approx. 65 kDa
    Gen-ID
    9356
    NCBI Accession
    NP_004781
    UniProt
    Q4U2R8
    Pathways
    Dicarboxylic Acid Transport
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