SLC22A6 Antikörper
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- Target Alle SLC22A6 Antikörper anzeigen
- SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC22A6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of OAT1 protein. (region surrounding Leu304)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography
- Reinheit
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product SLC22A6 Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
- Andere Bezeichnung
- SLC22A6 / OAT1 (SLC22A6 Produkte)
- Synonyme
- HOAT1 antikoerper, OAT1 antikoerper, PAHT antikoerper, ROAT1 antikoerper, NKT antikoerper, Oat1 antikoerper, Orctl1 antikoerper, mOat1 antikoerper, slc22a6 antikoerper, zgc:77073 antikoerper, SLC22A6 antikoerper, Paht antikoerper, Roat1 antikoerper, nkt antikoerper, oat1 antikoerper, oat1-B antikoerper, paht antikoerper, roat1 antikoerper, slc22a6-B antikoerper, Slc22a6 antikoerper, solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6, like antikoerper, Solute carrier family 22 member 6 antikoerper, solute carrier family 22 (organic anion transporter), member 6 S homeolog antikoerper, SLC22A6 antikoerper, Slc22a6 antikoerper, slc22a6l antikoerper, s22a6 antikoerper, slc22a6.S antikoerper
- Hintergrund
- SOAT1 (sterol O-acyltransferase 1), also designated ACAT1, is a homotetrameric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long-chain fatty acyl coenzyme A. The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol Oacyltransferase 2), also known as ACAT2 (acyl coenzyme A), participates in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the ER of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.Synonyms: Organic anion transporter 1, PAH transporter, PAHT, ROAT, Renal organic anion transporter 1, Solute carrier family 22 member 6
- Molekulargewicht
- approx. 65 kDa
- Gen-ID
- 9356
- NCBI Accession
- NP_004781
- UniProt
- Q4U2R8
- Pathways
- Dicarboxylic Acid Transport
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