Cathepsin B Antikörper
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- Target Alle Cathepsin B (CTSB) Antikörper anzeigen
- Cathepsin B (CTSB)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cathepsin B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of Cathepsin B protein. (region surrounding asn217)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product CTSB Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500approx. 1/1000. Immunohistochemistry on Paraffin Sections: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Cathepsin B (CTSB)
- Andere Bezeichnung
- Cathepsin B (CTSB Produkte)
- Synonyme
- APPS antikoerper, CPSB antikoerper, CB antikoerper, apps antikoerper, cpsb antikoerper, LOC692390 antikoerper, CTSB antikoerper, cathepsin B antikoerper, cathepsin B S homeolog antikoerper, CTSB antikoerper, Ctsb antikoerper, ctsb.S antikoerper, LOC692390 antikoerper
- Hintergrund
- The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S and O. The aspartyl protease class is composed of cathepsins D and E. cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.Synonyms: APP secretase, APPS, CPSB, CTSB, Cathepsin B1
- Molekulargewicht
- approx. 36 kDa
- Gen-ID
- 1508
- NCBI Accession
- NP_001899
- UniProt
- P07858
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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