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IL2 Receptor beta Antikörper
IL2RB
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-IL2 Receptor beta Antikörper
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Target
Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Reaktivität
Alle Reaktivitäten für IL2 Receptor beta Antikörper
Human
Wirt
Alle Wirte für IL2 Receptor beta Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IL2 Receptor beta Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL2 Receptor beta Antikörper
Dieser IL2 Receptor beta Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL2 Receptor beta Antikörper
Western Blotting (WB)
Spezifität
This antibody detects endogenous levels of IL-2Rβ protein. (region surrounding Leu90)
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography using epitope-specific immunogen
Reinheit
> 95 % (by SDS-PAGE)
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Anwendungsinformationen
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Applikationshinweise
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu IL2 Receptor beta
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Target
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Andere Bezeichnung
CD122 / IL2RB (IL2RB Produkte )
Synonyme
IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper
Hintergrund
IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
Molekulargewicht
approx. 60 kDa
Gen-ID
3560
NCBI Accession
NP_000869
UniProt
P14784
Pathways
JAK-STAT Signalweg , Growth Factor Binding
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