RPS6KA6 Antikörper

Produktnummer ABIN498435

Der Kaninchen Polyklonal anti-RPS6KA6 Antikörper (ABIN498435) detektiert spezifisch RPS6KA6 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RPS6KA6 Antikörper (ABIN498435)

Target: RPS6KA6 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 (RPS6KA6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RPS6KA6 Antikörper

Spezifität: This antibody detects endogenous levels of Rsk-4 protein. (region surrounding Gln688)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RPS6KA6

Target: RPS6KA6 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 (RPS6KA6))

Andere Bezeichnung: RPS6KA6 / RSK4

Hintergrund: The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The 70 kDa family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase beta, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rskrelated protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.Synonyms: 90 kDa ribosomal protein S6 kinase 6, RSK-4, Ribosomal S6 kinase 4, Ribosomal protein S6 kinase alpha-6, S6K-alpha-6, p90-RSK 6, p90RSK6, pp90RSK4

Molekulargewicht: approx. 84 kDa

Gen-ID: 27330

NCBI Accession: NP_055311

UniProt: Q9UK32

Pathways: MAPK Signalweg