HK3 Antikörper

Produktnummer ABIN498424

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HK3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HK3 Antikörper (ABIN498424)

Target: HK3 (Hexokinase 3 (White Cell) (HK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HK3 Antikörper

Spezifität: This antibody detects endogenous levels of HXK III protein. (region surrounding Val848)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HK3

Target: HK3 (Hexokinase 3 (White Cell) (HK3))

Andere Bezeichnung: Hexokinase-3

Hintergrund: Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.Synonyms: HK3, HKIII, Hexokinase type III

Molekulargewicht: approx. 99 kDa

Gen-ID: 3101

NCBI Accession: NP_002106

UniProt: P52790

Pathways: Carbohydrate Homeostasis, Warburg Effekt