LMX1B Antikörper

Produktnummer ABIN498413

Der Kaninchen Polyklonal anti-LMX1B Antikörper wird verwendet zum Nachweis von LMX1B in Proben von Human und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für LMX1B Antikörper (ABIN498413)

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMX1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LMX1B Antikörper

Spezifität: This antibody detects endogenous levels of LMX1B protein. (region surrounding Asp159)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Andere Bezeichnung: LMX1B

Hintergrund: The Lim class homeobox gene Lmx1b is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.Synonyms: LIM homeobox transcription factor 1-beta, LIM/homeobox protein 1.2, LIM/homeobox protein LMX1B, LMX-1.2, LMX1B

Molekulargewicht: approx. 42 kDa

Gen-ID: 4010

NCBI Accession: NP_002307

UniProt: O60663

Pathways: Dopaminergic Neurogenesis