Serotonin Receptor 1E Antikörper

Produktnummer ABIN498367

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Serotonin Receptor 1E in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Serotonin Receptor 1E Antikörper (ABIN498367)

Target: Serotonin Receptor 1E (HTR1E)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Serotonin Receptor 1E Antikörper

Spezifität: This antibody detects endogenous levels of SR-1E protein. (region surrounding Ala127)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Serotonin Receptor 1E

Target: Serotonin Receptor 1E (HTR1E)

Hintergrund: The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.Synonyms: 5-HT-1E, 5-HT1E, 5-hydroxytryptamine receptor 1E

Molekulargewicht: approx. 42 kDa

Gen-ID: 3354

NCBI Accession: NP_000856

UniProt: P28566

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process