14-3-3 zeta Antikörper

Produktnummer ABIN498366

Produktdetails anti-14-3-3 zeta Antikörper

Target: 14-3-3 zeta (YWHAZ)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 zeta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of 14-3-3 ζ protein. (region surrounding Ala79)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu 14-3-3 zeta

Target: 14-3-3 zeta (YWHAZ)

Andere Bezeichnung: 14-3-3 Protein zeta/delta (YWHAZ Produkte)

Synonyme: 14-3-3-zeta antikoerper, KCIP-1 antikoerper, YWHAD antikoerper, 14-3-3zeta antikoerper, Ywhaz antikoerper, ACYPI003154 antikoerper, 14-3-3z antikoerper, kcip-1 antikoerper, ywhaq antikoerper, 1433z antikoerper, ywhaz antikoerper, ywhazb antikoerper, 1110013I11Rik antikoerper, AI596267 antikoerper, AL022924 antikoerper, AU020854 antikoerper, ywhaza antikoerper, fb14h09 antikoerper, wu:fb05g08 antikoerper, wu:fb14h09 antikoerper, ywhai antikoerper, zgc:55807 antikoerper, 14-3-3 antikoerper, 14-3-3 zeta antikoerper, 14-3-3ZETA antikoerper, 14-3-3leo antikoerper, 2G1 antikoerper, 4-3-3 zeta antikoerper, 5.11 antikoerper, 549 antikoerper, BEST:GH05075 antikoerper, CG17870 antikoerper, D14-3-3 antikoerper, D14-3-3zeta antikoerper, Dmel\\CG17870 antikoerper, K antikoerper, LEO antikoerper, Leo antikoerper, PAR-5 antikoerper, PAR5 antikoerper, Par-5 antikoerper, d14-3-3zeta antikoerper, l(2)07103 antikoerper, l(2)46CFe antikoerper, l(2)46Ee antikoerper, leo antikoerper, par-5 antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antikoerper, 14-3-3 protein zeta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta L homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta S homeolog antikoerper, 14-3-3 protein zeta/delta pseudogene antikoerper, CG17870 gene product from transcript CG17870-RE antikoerper, YWHAZ antikoerper, 14-3-3zeta antikoerper, ywhaz antikoerper, 1433z antikoerper, ywhaz.L antikoerper, Ywhaz antikoerper, ywhaz.S antikoerper, LOC100855903 antikoerper

Hintergrund: 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, theta, epsilon, zeta, sigma and nu. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzyme activity etc.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAZ

Molekulargewicht: approx. 28 kDa

Gen-ID: 7534

NCBI Accession: NP_001129171

UniProt: P63104

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location