MELK Antikörper

Produktnummer ABIN498341

Produktdetails anti-MELK Antikörper

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MELK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MELK protein. (region surrounding asn449)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MELK

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Andere Bezeichnung: MELK (MELK Produkte)

Synonyme: MELK antikoerper, xmelk antikoerper, Melk antikoerper, HPK38 antikoerper, AI327312 antikoerper, MPK38 antikoerper, mKIAA0175 antikoerper, fb71b01 antikoerper, fe01f04 antikoerper, wu:fb71b01 antikoerper, wu:fe01f04 antikoerper, maternal embryonic leucine zipper kinase antikoerper, maternal embryonic leucine zipper kinase L homeolog antikoerper, MELK antikoerper, melk antikoerper, cgd5_2270 antikoerper, Melk antikoerper, melk.L antikoerper

Hintergrund: Maternal Embryonic Leucine Zipper Kinase (KIAA0175, HPK38) or MELK, a new member of the Snf1/AMPK family of kinases, encodes a protein with a kinase catalytic domain and a leucine zipper motif consisting of a periodic repetition of leucine residues at every seventh residue located within the N-terminal catalytic domain. This motif has been observed in myriad DNAbinding proteins and is presumed to be involved in protein-DNA interactions, and potentially protein-protein interactions. Research predicts that the gene product of MELK plays a role in the signal transduction events in the egg and early embryo. Mouse and human MELK proteins share 95 % sequence identity in the kinase domain and northern blot analysis in mouse indicates that MELK expression is restricted to spermatogonia in the testis and to oocytes in the ovary.Synonyms: KIAA0175, Maternal embryonic leucine zipper kinase, hMELK

Molekulargewicht: approx. 75 kDa

Gen-ID: 9833

NCBI Accession: NP_055606

UniProt: Q14680