Der Kaninchen Polyklonal anti-MYST2 Antikörper (ABIN498300) detektiert spezifisch MYST2 in WB und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
MYST2
(MYST Histone Acetyltransferase 2 (MYST2))
Andere Bezeichnung
MYST2
Hintergrund
KAT7 / Hbo1 is a member of the MYST histone acetyltransferae family which acetylates both histone H3 and H4 and is involved in the regulation of replication. The initiation of DNA replication is tightly regulated in eukaryotic cells to ensure that the genome is precisely duplicated once per cell cycle. This is accomplished by controlling the pre-replicative complex. KAT7 acts as a positive regulatory factor for pre-RC assembly and thus controls DNA replication.Synonyms: HBO1, HBOa, Histone acetyltransferase MYST2, Histone acetyltransferase binding to ORC1, MOZ, SAS2, TIP60 protein 2, YBF2/SAS3