MYST2 Antikörper (Internal Region)

Produktnummer ABIN6257254

Produktdetails anti-MYST2 Antikörper

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: MYST2 Antibody detects endogenous levels of total MYST2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MYST2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-MYST2 Antikörper (ABIN6257254)

Yang, Guan, Shaikh, Liang, Sun, Wang, Li, Qiu, Li: "Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 5, pp. 2159-2169, (2018) (PubMed).

Details zu MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Andere Bezeichnung: KAT7 (MYST2 Produkte)

Synonyme: Myst2 antikoerper, HBO1 antikoerper, HBOA antikoerper, MYST2 antikoerper, ZC2HC7 antikoerper, Hbo1 antikoerper, Hboa antikoerper, lysine acetyltransferase 7 antikoerper, K(lysine) acetyltransferase 7 antikoerper, MYST histone acetyltransferase 2 antikoerper, Kat7 antikoerper, KAT7 antikoerper, myst2 antikoerper

Hintergrund:

Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity). Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067). Specifically represses AR-mediated transcription.

Gene: KAT7

Molekulargewicht: 75 kDa

Gen-ID: 11143

UniProt: O95251