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ITGB1 Antikörper

ITGB1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498246
  • Target Alle ITGB1 Antikörper anzeigen
    ITGB1 (Integrin beta 1 (ITGB1))
    Reaktivität
    • 221
    • 112
    • 88
    • 22
    • 20
    • 20
    • 18
    • 12
    • 10
    • 10
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 159
    • 79
    • 20
    • 8
    • 8
    • 1
    Kaninchen
    Klonalität
    • 146
    • 124
    • 1
    Polyklonal
    Konjugat
    • 120
    • 25
    • 25
    • 16
    • 10
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser ITGB1 Antikörper ist unkonjugiert
    Applikation
    • 136
    • 123
    • 77
    • 50
    • 40
    • 31
    • 30
    • 27
    • 26
    • 21
    • 16
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody detects endogenous levels of ITGB1 protein.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography using epitope-specific immunogen
    Reinheit
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product ITGB1 Primärantikörper
  • Applikationshinweise
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Andere Bezeichnung
    CD29 / Integrin beta-1 (ITGB1 Produkte)
    Synonyme
    CD29 antikoerper, FNRB antikoerper, GPIIA antikoerper, MDF2 antikoerper, MSK12 antikoerper, VLA-BETA antikoerper, VLAB antikoerper, 4633401G24Rik antikoerper, AA409975 antikoerper, AA960159 antikoerper, ENSMUSG00000051907 antikoerper, Fnrb antikoerper, Gm9863 antikoerper, gpIIa antikoerper, cd29 antikoerper, fnrb antikoerper, gpiia antikoerper, itgb1 antikoerper, mdf2 antikoerper, msk12 antikoerper, vla-beta antikoerper, vlab antikoerper, itgb1-a antikoerper, itgb1-b antikoerper, integrin subunit beta 1 antikoerper, integrin beta 1 (fibronectin receptor beta) antikoerper, integrin subunit beta 1 S homeolog antikoerper, integrin beta 1 antikoerper, integrin subunit beta 1 L homeolog antikoerper, ITGB1 antikoerper, Itgb1 antikoerper, itgb1.S antikoerper, LOC100009173 antikoerper, itgb1.L antikoerper
    Hintergrund
    Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12
    Molekulargewicht
    approx. 135 kDa
    Gen-ID
    3688
    NCBI Accession
    NP_002202
    UniProt
    P05556
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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