ACLY Antikörper

Produktnummer ABIN498187

Produktdetails anti-ACLY Antikörper

Target: ACLY (ATP Citrate Lyase (ACLY))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACLY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous levels of ATP-citrate synthase protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Andere Bezeichnung: ATP-Citrate Synthase (ACLY Produkte)

Synonyme: ACLY antikoerper, DDBDRAFT_0205389 antikoerper, DDBDRAFT_0235360 antikoerper, DDB_0205389 antikoerper, DDB_0235360 antikoerper, ACL antikoerper, BcDNA:LD21334 antikoerper, CG8322 antikoerper, DmATPCL antikoerper, Dmel\\CG8322 antikoerper, anon-WO0140519.179 antikoerper, dATPCL antikoerper, l(2)01466 antikoerper, l(2)k09217 antikoerper, n(2)k09217 antikoerper, ATPCL antikoerper, CLATP antikoerper, A730098H14Rik antikoerper, AW538652 antikoerper, Clatp antikoerper, acly antikoerper, cb722 antikoerper, zgc:92008 antikoerper, ATP citrate lyase antikoerper, ATP citrate lyase S homeolog antikoerper, ATP-citrate synthase antikoerper, citrate synthase, mitochondrial antikoerper, atp-citrate synthase antikoerper, ATP citrate lyase a antikoerper, ACLY antikoerper, acly.S antikoerper, LOC587157 antikoerper, acly antikoerper, ATPCL antikoerper, LOC5564509 antikoerper, CpipJ_CPIJ010291 antikoerper, Bm1_26245 antikoerper, ACL antikoerper, Acly antikoerper, aclya antikoerper

Hintergrund: ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL.Synonyms: ACLY, ATP citrate (pro-S-)-lyase, Citrate cleavage enzyme

Molekulargewicht: approx. 120 kDa

Gen-ID: 47

NCBI Accession: NP_001087

UniProt: P53396

Pathways: Warburg Effekt