KSR1 Antikörper

Produktnummer ABIN498178

Produktdetails anti-KSR1 Antikörper

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KSR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of KSR protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu KSR1

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Andere Bezeichnung: Kinase Suppressor of Ras 1 (KSR1 Produkte)

Synonyme: CG2899 antikoerper, Dmel\\CG2899 antikoerper, EK3-1 antikoerper, KSR antikoerper, KSR-1 antikoerper, Ksr antikoerper, Ksr-1 antikoerper, SR3-1 antikoerper, dKsr antikoerper, l(3)j5E2 antikoerper, AW492498 antikoerper, B-KSR1 antikoerper, D11Bhm183e antikoerper, D11Bhm184e antikoerper, RSU2 antikoerper, hb antikoerper, kinase suppressor of ras 1 antikoerper, kinase suppressor of ras antikoerper, KSR1 antikoerper, ksr antikoerper, Ksr1 antikoerper

Hintergrund: Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFβ-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFβ stimulation.Synonyms: KSR, KSR-1, KSR1

Molekulargewicht: approx. 115 kDa

Gen-ID: 8844

NCBI Accession: NP_055053

UniProt: Q8IVT5