KSR1 Antikörper (AA 320-420)

Produktnummer ABIN7268119

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KSR1 in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KSR1 Antikörper (AA 320-420) (ABIN7268119)

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KSR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-KSR1 Antikörper

Bindungsspezifität: AA 320-420

Verwendungszweck: KSR1 Rabbit pAb

Sequenz: SSPAPFPTSS NPSSATTPPN PSPGQRDSRF NFPAAYFIHH RQQFIFPVPS AGHCWKCLLI AESLKENAFN ISAFAHAAPL PEAADGTRLD DQPKADVLEA H

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 320-420 of human KSR1 (NP_055053.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KSR1

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Andere Bezeichnung: KSR1

Hintergrund: Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity. Its kinase activity is unsure (By similarity. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity.,KSR1,KSR,RSU2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-Erk Signaling Pathway,KSR1

Molekulargewicht: 84kDa/87kDa/97kDa/102kDa

Gen-ID: 8844

UniProt: Q8IVT5