TTC8 Antikörper (Internal Region)

Produktnummer ABIN498031

Dieser Ziege Polyklonal Antikörper detektiert spezifisch TTC8 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Rind (Kuh), Hund und Schwein.

Kurzübersicht für TTC8 Antikörper (Internal Region) (ABIN498031)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TTC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TTC8 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-KEVLKQDNTH VE

Spezifität: This antibody is expected to recognize all reported isoforms (NP_653197.2, NP_938051.1, NP_938052.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine and Porcine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the Internal region of the protein sequence according to NP_653197.2, NP_938051.1, NP_938052.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.2-0.6 μg/mL. Approx 60 kDa band observed in Human Testis lysates(calculated MW of 58.0 kDa according to NP_653197.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Andere Bezeichnung: TTC8 / BBS8

Hintergrund: Defects in TTC8 are the cause of Bardet-Biedl syndrome type 8 (BBS8). This is a genetically heterogeneous, autosomal recessive disorder and the primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.Synonyms: Bardet-Biedl syndrome 8 protein, TPR repeat protein 8, Tetratricopeptide repeat protein 8

Gen-ID: 123016

NCBI Accession: NP_653197

UniProt: Q8TAM2

Pathways: Hedgehog Signalweg