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ATG10 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATG10 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN497986

Kurzübersicht für ATG10 Antikörper (C-Term) (ABIN497986)

Target

Alle ATG10 Antikörper anzeigen
ATG10 (Autophagy Related 10 (ATG10))

Reaktivität

  • 61
  • 14
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 59
  • 1
  • 1
Kaninchen

Klonalität

  • 58
  • 3
Polyklonal

Konjugat

  • 27
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG10 Antikörper ist unkonjugiert

Applikation

  • 25
  • 22
  • 20
  • 13
  • 13
  • 8
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    Recognizes APG10L/ATG10 (C-term).

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, Mouse and Rat

    Aufreinigung

    Immunoaffinity Chromatography

    Immunogen

    ATG10 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of Human ATG10 (Genbank accession No. EAW95884).

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: ATG10 antibody can be used for the detection of ATG10 at 0.5-1 μg/mL. Positive Control: SK-N-SH Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    ATG10 (Autophagy Related 10 (ATG10))

    Andere Bezeichnung

    APG10L / ATG10

    Hintergrund

    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.Synonyms: Autophagy-related protein 10

    Gen-ID

    83734

    NCBI Accession

    NP_001124500

    UniProt

    Q9H0Y0

    Pathways

    ER-Nucleus Signaling, Autophagie
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