Lamin B1 Antikörper (C-Term)

Produktnummer ABIN497968

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Lamin B1 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Lamin B1 Antikörper (C-Term) (ABIN497968)

Target: Lamin B1 (LMNB1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Lamin B1 Antikörper

Bindungsspezifität: AA 466-496, C-Term

Spezifität: Recognizes Lamin B1 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-496 amino acids from the C-terminal region of Human Lamin B1. Genename: LMNB1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000Western blotting: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin-B1 (LMNB1)

Hintergrund: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.Synonyms: LMN2, LMNB, LMNB-1, LMNB1, Lamin-B1, Nuclear Envelope Marker

Gen-ID: 4001

NCBI Accession: NP_005564

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose