RORC Antikörper

Produktnummer ABIN4966337

Der Kaninchen Polyklonal Anti-RORC-Antikörper wurde für WB validiert. Er ist geeignet, RORC in Proben von Arabidopsis thaliana zu detektieren.

Kurzübersicht für RORC Antikörper (ABIN4966337)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reaktivität: Arabidopsis thaliana

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RORC Antikörper

Kreuzreaktivität (Details): Not reactive in: Chlamydomonas reinhardtii

Homologie: Glycine max, Oryza sativa, Physcomitrella patens, Populus trichocarpa, Setaria italica, Sorghum bicolor, Zea mays, Vitis vinifera

Immunogen: KLH-conjugated synthetic peptide derived from Arabidopsis thaliana TOR protein sequence, UniProt: Q9FR53, TAIR: AT1G50030

Anwendungsinformationen

Applikationshinweise: 1 : 5000 with standard ECL (WB)

Kommentare:

TOR is a subjected to post-translational modifications (ubiquitination and phosphorylation), which can change the migration pattern in SDS gel.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μL of sterile water.

Lagerung: -20 °C

Informationen zur Lagerung: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: Target of rapamycin (TOR)

Hintergrund: TOR (Target of rapamycin) is an essential cell growth regulator that controls development from early embryo to seed production in response to nutrient availability in envoronmental stress conditions. It belongs to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR is expressed in embryos, endosperm and meristems. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.

Molekulargewicht: 279 kDa

UniProt: Q9FR53

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway