Cadherin 5 Antikörper (AA 106-134)

Produktnummer ABIN3030247

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cadherin 5 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cadherin 5 Antikörper (AA 106-134) (ABIN3030247)

Target: Cadherin 5 (CDH5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Cadherin 5 Antikörper

Bindungsspezifität: AA 106-134

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the VE Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the VE Cadherin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: VE Cadherin (CDH5)

Hintergrund: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2