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UCHL3 Antikörper (AA 195-225)

Uchl3 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029426
  • Target Alle UCHL3 (Uchl3) Antikörper anzeigen
    UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 195-225
    Reaktivität
    • 60
    • 43
    • 25
    • 9
    • 9
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 60
    • 5
    • 1
    Kaninchen
    Klonalität
    • 61
    • 5
    Polyklonal
    Konjugat
    • 36
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UCHL3 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 21
    • 16
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Pig
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 195-225 from the human protein was used as the immunogen for this UCHL3 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product Uchl3 Primärantikörper
  • Applikationshinweise
    Titration of the UCHL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the UCHL3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))
    Andere Bezeichnung
    UCHL3 (Uchl3 Produkte)
    Synonyme
    UCH-L3 antikoerper, UCH-6 antikoerper, RGD1561196 antikoerper, im:6908825 antikoerper, zgc:109963 antikoerper, uchl4 antikoerper, ubiquitin C-terminal hydrolase L3 antikoerper, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) antikoerper, ubiquitin C-terminal hydrolase L3 L homeolog antikoerper, UCHL3 antikoerper, Uchl3 antikoerper, uchl3 antikoerper, uchl3.L antikoerper
    Hintergrund
    Covalent attachment of the C-terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs). Mayer and Wilkinson (1989) identified 4 distinct UCH activities from bovine thymus. All 4 were thiol proteases and had high-affinity binding sites for ubiquitin. Wilkinson et al. (1989) purified the predominant isozyme, UCHL3, and raised antibodies against it. By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. Sequence comparisons revealed that the sequence of the predicted 230-amino acid human UCHL3 protein is 54 % identical to that of UCHL1.
    UniProt
    P15374
    Pathways
    Feeding Behaviour, Positive Regulation of fat Cell Differentiation
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