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Ubiquitin Antikörper (AA 36-66)

Der Kaninchen Polyklonal Anti-Ubiquitin-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet, Ubiquitin in Proben von Human zu detektieren.
Produktnummer ABIN3029420

Kurzübersicht für Ubiquitin Antikörper (AA 36-66) (ABIN3029420)

Target

Alle Ubiquitin (Ub) Antikörper anzeigen
Ubiquitin (Ub)

Reaktivität

  • 175
  • 73
  • 72
  • 67
  • 20
  • 17
  • 17
  • 16
  • 16
  • 16
  • 12
  • 12
  • 11
  • 10
  • 10
  • 9
  • 9
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 107
  • 94
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 114
  • 92
Polyklonal

Konjugat

  • 85
  • 15
  • 11
  • 10
  • 10
  • 9
  • 7
  • 7
  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Ubiquitin Antikörper ist unkonjugiert

Applikation

  • 179
  • 113
  • 83
  • 59
  • 57
  • 46
  • 30
  • 30
  • 26
  • 21
  • 13
  • 13
  • 9
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 30
    • 18
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-66

    Kreuzreaktivität (Details)

    Expected species reactivity: Bovine, C. elegans, Chicken, Drosophila, Mouse, Pig, Primate, Rat,Yeast

    Aufreinigung

    Purified

    Immunogen

    A portion of amino acids 36-66 from the human protein was used as the immunogen for this Ubiquitin antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the Ubiquitin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the Ubiquitin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Ubiquitin (Ub)

    Andere Bezeichnung

    Ubiquitin

    Hintergrund

    This gene encodes Ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

    UniProt

    P0CG48

    Pathways

    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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