TXNIP Antikörper (AA 116-145)
Kurzübersicht für TXNIP Antikörper (AA 116-145) (ABIN3029123)
Target
Alle TXNIP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 116-145
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Kreuzreaktivität (Details)
- Expected species reactivity: Rat
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 116-145 from the mouse protein was used as the immunogen for this Txnip antibody.
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Isotyp
- Ig Fraction
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anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibodyTXNIP Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibodyTXNIP Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB30652 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibodyTXNIP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibodyTXNIP Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf, Affe, Fledermaus, Schwein, Xenopus laevis WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the Txnip antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Txnip antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Andere Bezeichnung
- Txnip
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Hintergrund
- May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. [UniProt]
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UniProt
- Q8BG60
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Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
Target
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