TSC1 Antikörper (AA 1117-1144)
Kurzübersicht für TSC1 Antikörper (AA 1117-1144) (ABIN3029279)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1117-1144
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 1117-1144 from the mouse protein was used as the immunogen for this TSC1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the TSC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- TSC1
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Hintergrund
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
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UniProt
- Q9EP53
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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