TRAF4 Antikörper (AA 427-455)

Produktnummer ABIN3029152

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRAF4 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRAF4 Antikörper (AA 427-455) (ABIN3029152)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRAF4 Antikörper

Bindungsspezifität: AA 427-455

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 427-455 from the human protein was used as the immunogen for this TRAF4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TRAF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Andere Bezeichnung: TRAF4

Hintergrund: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

UniProt: Q9BUZ4