TFAM Antikörper (AA 216-246)

Produktnummer ABIN3029196

Der Kaninchen Polyklonal anti-TFAM Antikörper (ABIN3029196) detektiert spezifisch TFAM in WB, IHC, ELISA, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TFAM Antikörper (AA 216-246) (ABIN3029196)

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-TFAM Antikörper

Bindungsspezifität: AA 216-246

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 216-246 from the human protein was used as the immunogen for this TFAM antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TFAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TFAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: TFAM

Hintergrund: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.

UniProt: Q00059

Pathways: Chromatin Binding