SYK Antikörper (AA 195-223)
Kurzübersicht für SYK Antikörper (AA 195-223) (ABIN3032716)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 195-223
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Kreuzreaktivität (Details)
- Expected species reactivity: Chicken, Rat
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 195-223 from the mouse protein was used as the immunogen for this Syk antibody.
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Isotyp
- Ig Fraction
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anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reaktivität: Human, Maus, Ratte WB, IP, IHC (p), ICC Wirt: Maus Monoclonal SYK-01 unconjugated
anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibodySYK Reaktivität: Human, Maus, Ratte WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2G11E6 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D1G10 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibodySYK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03097 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibodySYK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibodySYK Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Syk antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- Syk
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Hintergrund
- Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
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UniProt
- P48025
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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