SUMO4 Antikörper

Produktnummer ABIN3032653

Produktdetails anti-SUMO4 Antikörper

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUMO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: This SUMO4 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human SUMO4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SUMO4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SUMO4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SUMO4

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Andere Bezeichnung: SUMO4 (SUMO4 Produkte)

Synonyme: IDDM5 antikoerper, SMT3H4 antikoerper, SUMO-4 antikoerper, dJ281H8.4 antikoerper, small ubiquitin-like modifier 4 antikoerper, small ubiquitin-related modifier 4 antikoerper, SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) antikoerper, SUMO4 antikoerper, sumo4 antikoerper

Hintergrund: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. [UniProt]

UniProt: Q6EEV6