SUMO2/3 Antikörper (AA 49-81)

Produktnummer ABIN3032650

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SUMO2/3 in WB, IF, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SUMO2/3 Antikörper (AA 49-81) (ABIN3032650)

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUMO2/3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SUMO2/3 Antikörper

Bindungsspezifität: AA 49-81

Kreuzreaktivität (Details): Expected species reactivity: Bovine, Chicken, Hamster, Pig, Primate, Rat, Xenopus, Zebrafish

Aufreinigung: Purified

Immunogen: A portion of amino acids 49-81 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25-100,Western blot: 1:1000,IHC (FFPE): 1:50-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SUMO2/3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SUMO2/3

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Andere Bezeichnung: SUMO2/3

Hintergrund: SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

UniProt: P55854