SUMO2 Antikörper

Produktnummer ABIN3032647

Dieser Maus Monoklonal Antikörper detektiert spezifisch SUMO2 in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für SUMO2 Antikörper (ABIN3032647)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SUMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 973CT8-1-1

Produktdetails anti-SUMO2 Antikörper

Verwendungszweck: SUMO-2 Antibody

Kreuzreaktivität (Details): Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate

Aufreinigung: Purified

Immunogen: Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SUMO-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Andere Bezeichnung: SUMO-2

Hintergrund: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

UniProt: P61956

Pathways: Methionine Biosynthetic Process