SUMO2 Antikörper

Produktnummer ABIN3032647

Produktdetails anti-SUMO2 Antikörper

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SUMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität (Details): Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate

Aufreinigung: Purified

Immunogen: Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.

Klon: 973CT8-1-1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SUMO-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Andere Bezeichnung: SUMO-2 (SUMO2 Produkte)

Synonyme: HSMT3 antikoerper, SMT3B antikoerper, SMT3H2 antikoerper, SUMO3 antikoerper, Smt3A antikoerper, SMT3A antikoerper, SMT3H1 antikoerper, SUMO-3 antikoerper, Smt3B antikoerper, Smt3h2 antikoerper, sumo2 antikoerper, zgc:92241 antikoerper, SUMO2 antikoerper, SUMO-2 antikoerper, Smt3b antikoerper, hsmt3 antikoerper, smt3b antikoerper, smt3h2 antikoerper, sumo-2 antikoerper, PSMT3 antikoerper, ATSUMO2 antikoerper, MCO15.11 antikoerper, MCO15_11 antikoerper, SMALL UBIQUITIN-LIKE MODIFIER 2 antikoerper, SUM2 antikoerper, SUMO 2 antikoerper, small ubiquitin-like modifier 2 antikoerper, small ubiquitin-like modifier 2 antikoerper, small ubiquitin-like modifier 3 antikoerper, small ubiquitin-like modifier 2b antikoerper, small ubiquitin-related modifier 2 antikoerper, small ubiquitin-like modifier 2 S homeolog antikoerper, small ubiquitin-like modifier 2 L homeolog antikoerper, SUMO2 antikoerper, SUMO3 antikoerper, Sumo2 antikoerper, sumo2b antikoerper, LOC714892 antikoerper, sumo2.S antikoerper, sumo2.L antikoerper

Hintergrund: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

UniProt: P61956

Pathways: Methionine Biosynthetic Process