Der Kaninchen Polyklonal anti-SOCS4 Antikörper (ABIN3029046) detektiert spezifisch SOCS4 in WB, ELISA, IHC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the SOCS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
SOCS4
(Suppressor of Cytokine Signaling 4 (SOCS4))
Andere Bezeichnung
SOCS4
Hintergrund
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]