RUNX1 Antikörper (C-Term)

Produktnummer ABIN3032497

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RUNX1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RUNX1 Antikörper (C-Term) (ABIN3032497)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RUNX1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Expected species reactivity: Xenopus

Aufreinigung: Antigen affinity purified

Immunogen: This RUNX1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 421-455 amino acids from the C-terminal region of human RUNX1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RUNX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RUNX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1

Hintergrund: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.

UniProt: Q01196