Rhodopsin Antikörper (AA 310-339)

Produktnummer ABIN3032473

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Rhodopsin in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rhodopsin Antikörper (AA 310-339) (ABIN3032473)

Target: Rhodopsin (RHO)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rhodopsin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Rhodopsin Antikörper

Bindungsspezifität: AA 310-339

Kreuzreaktivität (Details): Expected species reactivity: Primate

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Rhodopsin

Target: Rhodopsin (RHO)

Andere Bezeichnung: rho (Rhodopsin)

Substanzklasse: Chemical

Hintergrund: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

UniProt: P08100

Pathways: WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction