Ret Proto-Oncogene Antikörper (AA 1012-1042)

Produktnummer ABIN3032460

Dieses Anti-Ret Proto-Oncogene-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ret Proto-Oncogene in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für Ret Proto-Oncogene Antikörper (AA 1012-1042) (ABIN3032460)

Target: Ret Proto-Oncogene (RET)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Ret Proto-Oncogene Antikörper

Bindungsspezifität: AA 1012-1042

Aufreinigung: Purified

Immunogen: A portion of amino acids 1012-1042 from the human protein was used as the immunogen for this RET antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RET antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RET antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Andere Bezeichnung: RET

Hintergrund: RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.

UniProt: P07949

Pathways: RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation