RBPMS Antikörper (AA 166-193)

Produktnummer ABIN3032494

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RBPMS in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RBPMS Antikörper (AA 166-193) (ABIN3032494)

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBPMS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RBPMS Antikörper

Bindungsspezifität: AA 166-193

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RBPMS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RBPMS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Andere Bezeichnung: RBPMS

Hintergrund: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

UniProt: Q93062