Retinoblastoma Protein (Rb) Antikörper (AA 586-615)
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- Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Bindungsspezifität
- AA 586-615
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product Rb Protein Primärantikörper
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anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein Reaktivität: Human ELISA, IHC, IF, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibodyRb Protein Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibodyRb Protein Reaktivität: Human, Maus WB, IHC Wirt: Maus Monoclonal 172C1094 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibodyRb Protein Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibodyRb Protein Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibodyRb Protein Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) antibodyRb Protein Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 7E4B8 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibodyRb Protein Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Schwein, Fledermaus, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibodyRb Protein Reaktivität: Human, Maus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibodyRb Protein Reaktivität: Human, Rind (Kuh), Hund, Schwein, Fledermaus, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Andere Bezeichnung
- Rb (Retinoblastoma) (Rb Protein Produkte)
- Hintergrund
- The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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