Der Kaninchen Polyklonal anti-RAGE Antikörper (ABIN3029883) detektiert spezifisch RAGE in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Rage antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))
Andere Bezeichnung
Rage
Hintergrund
RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]