Progesterone Receptor Antikörper (AA 816-843)
Kurzübersicht für Progesterone Receptor Antikörper (AA 816-843) (ABIN3029751)
Target
Alle Progesterone Receptor (PGR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 816-843
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Verwendungszweck
- PR Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 816-843 from the human protein was used as the immunogen for this PR antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the PR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Progesterone Receptor (PGR)
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Andere Bezeichnung
- Progesterone Receptor
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Hintergrund
- This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
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UniProt
- P06401
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Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Target
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