TSC1 Antikörper (pSer312)

Produktnummer ABIN3029286

Dieses Anti-TSC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TSC1 in DB und ELISA. Geeignet für Ratte.

Kurzübersicht für TSC1 Antikörper (pSer312) (ABIN3029286)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSC1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB), ELISA

Produktdetails anti-TSC1 Antikörper

Bindungsspezifität: pSer312

Aufreinigung: Antigen affinity purified

Immunogen: This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of rat TSC1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the phospho-TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the phospho-TSC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Andere Bezeichnung: TSC1

Hintergrund: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

UniProt: Q9Z136

Pathways: RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation