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PDX1 Antikörper (AA 136-169)
PDX1
Reaktivität: Maus
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN3032147
Produktdetails anti-PDX1 Antikörper
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Target
Alle PDX1 Antikörper anzeigen
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Bindungsspezifität
Alle Epitope für PDX1 Antikörper
AA 136-169
Reaktivität
Alle Reaktivitäten für PDX1 Antikörper
Maus
Wirt
Alle Wirte für PDX1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PDX1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PDX1 Antikörper
Dieser PDX1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PDX1 Antikörper
Western Blotting (WB), ELISA
Aufreinigung
Antigen affinity purified
Immunogen
This mouse Pdx1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 136-169 amino acids from the Central region of mouse Pdx1.
Isotyp
Ig Fraction
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Discover our top product PDX1 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Titration of the Pdx1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Pdx1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Details zu PDX1
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Target
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Andere Bezeichnung
Pdx1 (PDX1 Produkte )
Synonyme
GSF antikoerper, IDX-1 antikoerper, IPF1 antikoerper, IUF1 antikoerper, MODY4 antikoerper, PDX-1 antikoerper, STF-1 antikoerper, ipf1 antikoerper, PDX1 antikoerper, IPF-1 antikoerper, Ipf1 antikoerper, Mody4 antikoerper, pdx-1 antikoerper, Idx1 antikoerper, Stf1 antikoerper, zgc:100874 antikoerper, XlHbox-8 antikoerper, xlhbox8 antikoerper, pancreatic and duodenal homeobox 1 antikoerper, pancreatic and duodenal homeobox 1 S homeolog antikoerper, PDX1 antikoerper, pdx1 antikoerper, Pdx1 antikoerper, pdx1.S antikoerper
Hintergrund
Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
UniProt
P52946
Pathways
Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Hormone Transport , Carbohydrate Homeostasis , Chromatin Binding , Maintenance of Protein Location
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