PDGFRA Antikörper (AA 698-727)

Produktnummer ABIN3032255

Der Kaninchen Polyklonal Anti-PDGFRA Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, PDGFRA in Proben von Human zu detektieren.

Kurzübersicht für PDGFRA Antikörper (AA 698-727) (ABIN3032255)

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PDGFRA Antikörper

Bindungsspezifität: AA 698-727

Kreuzreaktivität (Details): Expected species reactivity: Chicken, Mouse, Rat, Xenopus

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 698-727 from the human alpha protein was used as the immunogen for this PDGFR antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PDGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PDGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PDGFRA

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Hintergrund: As a receptor for PDGFA, PDGFR alpha promotes or inhibits cell proliferation and cell migration. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. [UniProt]

UniProt: P16234

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling