PAK4 Antikörper (AA 187-216)
Kurzübersicht für PAK4 Antikörper (AA 187-216) (ABIN3032118)
Target
Alle PAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 187-216
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the Pak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Pak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- PAK4 (P21-Activated Kinase 4 (PAK4))
-
Andere Bezeichnung
- Pak4
-
Hintergrund
- Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
-
UniProt
- Q8BTW9
-
Pathways
- RTK Signalweg
Target
-