NRF1 Antikörper (AA 226-255)

Produktnummer ABIN3032068

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NRF1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NRF1 Antikörper (AA 226-255) (ABIN3032068)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NRF1 Antikörper

Bindungsspezifität: AA 226-255

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Zebrafish

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 226-255 from the human protein was used as the immunogen for this NRF1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Andere Bezeichnung: NRF1

Hintergrund: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha