NKX3-1 Antikörper (AA 3-1)

Produktnummer ABIN3032012

Der Kaninchen Polyklonal Anti-NKX3-1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, NKX3-1 in Proben von Maus zu detektieren.

Kurzübersicht für NKX3-1 Antikörper (AA 3-1) (ABIN3032012)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKX3-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NKX3-1 Antikörper

Bindungsspezifität: AA 3-1

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Nkx3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Andere Bezeichnung: Nkx3.1

Hintergrund: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.

UniProt: P97436

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus