Der Kaninchen Polyklonal Anti-NK2 Homeobox 5-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, NK2 Homeobox 5 in Proben von Maus und Ratte zu detektieren.
This mouse Nkx2.5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 192-225 amino acids from the Central region of human mouse Nkx2.5.
Titration of the Nkx2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Nkx2.5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
NK2 Homeobox 5 (NKX2-5)
Andere Bezeichnung
Nkx2.5
Hintergrund
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.