NCAPH2 Antikörper (AA 198-227)
-
- Target Alle NCAPH2 Antikörper anzeigen
- NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
-
Bindungsspezifität
- AA 198-227
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NCAPH2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NCAPH2 Primärantikörper
-
-
- Applikationshinweise
- Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the NCAPH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
- Andere Bezeichnung
- NCAPH2 (NCAPH2 Produkte)
- Hintergrund
- Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
- UniProt
- Q6IBW4
-