MUSK Antikörper (AA 35-65)

Produktnummer ABIN3031877

Der Kaninchen Polyklonal Anti-MUSK-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, MUSK in Proben von Human zu detektieren.

Kurzübersicht für MUSK Antikörper (AA 35-65) (ABIN3031877)

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUSK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-MUSK Antikörper

Bindungsspezifität: AA 35-65

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 35-65 from the human protein was used as the immunogen for this MUSK antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Andere Bezeichnung: MUSK

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: O15146

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development