MMP2 Antikörper (AA 303-331)

Produktnummer ABIN3031729

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MMP2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MMP2 Antikörper (AA 303-331) (ABIN3031729)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MMP2 Antikörper

Bindungsspezifität: AA 303-331

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Chicken, Rabbit

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 303-331 from the human protein was used as the immunogen for this MMP2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P08253

Pathways: Activation of Innate immune Response