MMP14 Antikörper (AA 470-499)

Produktnummer ABIN3031714

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MMP14 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MMP14 Antikörper (AA 470-499) (ABIN3031714)

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 133CT15-10-5-1

Produktdetails anti-MMP14 Antikörper

Bindungsspezifität: AA 470-499

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Rabbit

Aufreinigung: Purified

Immunogen: A portion of amino acids 470-499 from the human protein was used as the immunogen for this MMP14 antibody.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MMP14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Andere Bezeichnung: MMP14

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

UniProt: P50281

Pathways: Autophagie