MITF Antikörper (AA 1-28)

Produktnummer ABIN3031775

Der Kaninchen Polyklonal Anti-MITF-Antikörper wurde für WB, IF, FACS und ELISA validiert. Er ist geeignet, MITF in Proben von Human zu detektieren.

Kurzübersicht für MITF Antikörper (AA 1-28) (ABIN3031775)

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MITF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

Produktdetails anti-MITF Antikörper

Bindungsspezifität: AA 1-28

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-28 from the human protein was used as the immunogen for this MITF antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MITF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MITF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MITF

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Andere Bezeichnung: MITF

Hintergrund: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: O75030

Pathways: Chromatin Binding